Replay Holdings LLC

Replay Holdings LLC is a genome writing company based in San Diego, California. The company employs 50 people and has generated over $10,000 in revenue. Replay Holdings LLC focuses on reprogramming biology through the writing and delivery of large DNA sequences, aiming to advance the field of genomic medicine. Replay develops disruptive platform technologies, including high payload capacity HSV platforms, hypoimmunogenic platforms, and genome writing platforms. These technologies address scientific challenges hindering clinical progress in genomic medicine. The company operates under a hub-and-spoke business model, separating technology development from therapeutic development in its product companies. One of Replay's key technologies is synHSV™, a high-capacity HSV vector capable of delivering 30 times more genetic material than AAV vectors. This technology is utilized by four of Replay's gene therapy product companies, which are developing treatments for diseases affecting the skin, eye, brain, and muscle. Replay has also established a product company specializing in enzyme writing, leveraging its evolutionary inference machine learning and genome writing technology to enhance enzyme functionality. For more information about Replay Holdings LLC and its groundbreaking technologies, please visit their website at replay.bio.